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Hydrator / Humectant

Acetyl Hexapeptide-37

Often labeled as: Diffuporine

The aquaporin-boosting hydration peptide.

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Overall Safety Safe
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Pregnancy Safety Safe
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Comedogenic (0-5) 0 / 5
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Irritancy (0-5) 0 / 5

๐Ÿ”ฌ How It Actually Works

A hexapeptide that specifically targets Aquaporin-3 (AQP3) in the skin. AQP3 channels transport water from the basal layer to the stratum corneum; this peptide increases their production dramatically.

๐Ÿ’– Why your skin loves it

Improves inner skin hydration, rejuvenates mature skin, and stops flaking.

๐Ÿ’ก Pro Tip

Provides moisture from within, rather than just trapping it on top.

โš–๏ธ Myth vs. Fact

The Myth

It acts as an occlusive.

The Science

It works entirely through cellular signaling to improve your body's own water transport.