Dr Anne Β· Serum

10% Argireline Serum with NAD+

πŸ§ͺ pH 5.5 β˜€οΈπŸŒ™ AM & PM
Formulated For
Focus: Fine Lines, Wrinkles, Crow's Feet, Smile Lines
9.2
Glowwe Score β˜…β˜…β˜…β˜…β˜…
10% Argireline Serum with NAD+
Reality Check

Claims vs. Reality

A lightweight argireline serum for those looking for targeted skincare for expression lines. Enriched with 10% argireline and NAD+ to support smoother-looking skin and hydration. Ideal for daily use on areas such as the forehead, smile lines, and crow's feet.

Glowwe Verdict

An exceptionally focused anti-aging treatment designed to target dynamic wrinkles. It leverages a clinical 10 percent dose of Acetyl Hexapeptide-8 (Argireline), an elite neuropeptide famously known as Botox in a bottle, which works to gently relax facial muscle tension. By pairing this with cutting-edge NAD+ (Nicotinamide Adenine Dinucleotide) to boost cellular energy, this fluid acts as a formidable defense against deep forehead creases and smile lines.

"Targeted skincare for expression lines like forehead, smile lines, and crow's feet."True

The Reality: The extreme 10 percent concentration of Argireline directly intercepts neurotransmitter signals, subtly relaxing the repetitive muscle movements that etch deep dynamic wrinkles over time cleanly.

"Permanently erases structural deep physical atrophic pitted acne scars overnight."False

The Reality: The peptide serum beautifully softens expression lines, but deep structural scar indentations require clinical subcision loops entirely.

"Supports smoother-looking skin and hydration."True

The Reality: The inclusion of Sodium Hyaluronate and Cucumber extract swells the epidermal layers with water, immediately plumping and blurring the appearance of fine static lines flawlessly.

πŸ‘ Formulator Pros

  • Delivers an exceptionally high clinical concentration of Acetyl Hexapeptide-8 specifically proven to target dynamic facial wrinkles.
  • Incorporates highly advanced NAD+ technology, a rare and premium cellular energy booster typically found in luxury bio-hacking treatments.
  • Water-light fluid consistency absorbs instantly without utilizing heavy silicones, preventing any massive cosmetic pilling.

πŸ‘Ž Potential Downsides

  • Contains synthetic masking fragrances which completely contradicts modern sensitive-skin formulation standards.
  • Peptides require continuous, daily application to maintain the muscle-relaxing effect; stopping usage will cause wrinkles to slowly return.
  • The premium formulation comes with a significantly higher price tag compared to standard basic hydration serums.
Matchmaker

Is This Right for You?

Verify this formulation matches your specific skin profile before buying.

Free From vs. Contains
Free From Drying Alcohol
Contains Synthetic Fragrance
Free From Essential Oils
Free From Parabens
Free From Silicone-Free
Free From Oils
Profile Suitability
Aging Profiles with Dynamic Expression Lines βœ… Yes The high-dose Argireline peptide acts as a non-invasive topical muscle relaxant, visibly softening the depth of forehead creases and crow's feet effectively.
Preventative Anti-Aging Routines βœ… Yes Supplying NAD+ to the cellular matrix enhances mitochondrial energy, promoting long-term structural resilience and youthfulness perfectly.
Extremely Reactive and Fragrance-Sensitive Barriers ⚠️ Caution The formula contains added synthetic fragrance which can trigger localized stinging cascades on highly allergic or raw skin maps.

βœ… Perfect Match

Users with Deep Forehead and Smile Lines The neuropeptide matrix actively softens the repetitive facial tension that causes these specific deep creases smoothly.
Individuals Seeking Botox Alternatives Provides a highly effective, needle-free topical approach to relaxing facial expression muscles flawlessly.
Daily Makeup Wearers The lightweight water matrix absorbs flawlessly flat, preventing any foundation pilling safely.

❌ Better Avoid

Fragrance Sensitive Profiles Individuals with known allergies to cosmetic perfumes must avoid this formulation to prevent contact dermatitis entirely.
People wanting an overnight miracle Topical peptides take at least 4 to 8 weeks of daily accumulation to visibly relax muscle tension; they are not instant magic fillers.
Texture Profile

How It Feels & Absorbs

Thickness Lightweight Translucent Fluid Serum
Greasiness None
Stickiness Low (Slight tackiness before drying flat)
Absorption Fast (~15 secs)
Silicone Feel None
Scent Intensity Medium Synthetic Clean Perfume
Routine Guide

How to Layer It

Step placement, ingredient interactions, and what to expect over time.

🧼
Cleanser
πŸ’§
Hydrating Toner
πŸ§ͺ
This Formula (Anti-Aging Peptide Serum Step)
🧴
Moisturizer Cream
β˜€οΈ
SPF (AM Mandatory)
⏱ Formulator Note

To maximize the muscle-relaxing benefits of this premium serum, apply it directly onto slightly damp skin immediately after your toner. Press it firmly into your deep expression lines for 10 seconds to force the peptides down into the skin.

Can Combine With

🀝
Ceramide Barrier CreamsThe ultimate skin barrier blueprint for PM routines: active peptide repair from this serum, sealed flat immediately with emollient lipid bricks flawlessly.

Enemies β€” Do Not Mix

⚠️
High Percentage Leave-On Glycolic Acid (Same routine)Directly stacking pure low-pH peeling solutions over delicate peptide chains can denature the proteins, rendering the Argireline completely useless entirely.

⏳ Timeline Expectations

Day 1
Skin surface layout feels intensely hydrated, deeply refreshed, and fine dehydration lines immediately look plumper safely.
1 Week
The skin matrix feels slightly more resilient and bouncy due to the continuous hydration and NAD+ cellular energy boost.
4 Weeks
Dynamic expression lines around the eyes and forehead begin to visually soften as the neuropeptide accumulates and relaxes tension.
8 Weeks
Global dermal landscape achieves a beautifully smoothed, youthfully relaxed baseline structure completely guarded from deepening creases safely.
Ingredient Breakdown

Inside the Bottle

Heroes and formulation notes β€” not just the raw INCI list. Hover chips for details.

The Heavy Lifters
Anti-aging
Live INCI Decoder

Full Formula Scan

Automatically parsed and cross-referenced with the Glowwe Lab database.

#IngredientWhat It DoesSafetyIrr / Com
01 Aqua Solvent / Base The pure water solvent base. Safe 0 / 0
02 Glycerin Hydrator / Humectant A natural skin-identical moisture sponge. Safe 0 / 0
03 Propanediol Hydrator / Humectant The natural, skin-friendly alternative to Propylene Glycol. Safe 0 / 0
04 Acetyl Hexapeptide-8 Active Ingredients The original "Botox in a bottle". Safe 0 / 0
05 Nicotinamide Adenine Dinucleotide (NAD+) Pending Data Awaiting lab classification. Unknown - / -
06 Cucumis Sativus (Cucumber) Fruit Extract Pending Data Awaiting lab classification. Unknown - / -
FAQ

Common Questions

What the community asks most β€” answered with formulation facts.

Is this really like Botox in a bottle?
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Argireline (Acetyl Hexapeptide-8) is a neuropeptide that works similarly to Botox by interfering with the signals that cause muscle contractions. While a topical serum will never freeze your face completely like an injection, consistent use at 10 percent concentration will significantly and visibly soften expression lines safely.

Can I use it with my Vitamin C or AHA toners?
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We recommend caution. Strong acids (like low-pH Glycolic acid or pure L-Ascorbic Acid) can potentially break down the delicate peptide chains. If you use strong acids, apply them in the morning and save this Peptide serum strictly for your night routine cleanly.

Where exactly should I apply it?
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While you can apply it all over, it is best used as a targeted treatment! Press a few drops directly into your forehead lines, the crow's feet around your eyes, and your smile lines smoothly.

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